DBSCR - Regulated genes

   Database of transcriptional regulation in Streptomyces coelicolor

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Regulated gene: alpZ

Operon: No data
Genes Gene ID Synonyms Function
alpZ


Promoters

Binding
factor
Promoter
name
Regulation Location Binding seq.(cis-element) Experimental evidence Organism
AlpZ - Negative -86:-61 (from translational start site) GAAAATACGGACTCCCTGGTTTTGTT Bunet R, et al. (2008): DB, GS, SDM, RT-PCR
S. ambofaciens

Comments:
AlpZ Deletion of the two copies of alpZ resulted in the precocious production of both alpomycin and the orange pigment, suggesting a repressor role for AlpZ. Furthermore, recombinant AlpZ was shown to bind to specific DNA sequences within the promoter regions of alpZ, alpV, and alpXW, suggesting direct transcriptional control of these genes by AlpZ. AlpZ binds to a specific DNA sequence that resembles the ARE motifs recognized by typical gamma-butyrolactone receptors.


Terminator

No Data




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Contact: Yuko Makita