DBSCR - Transcription factor

   Database of transcriptional regulation in Streptomyces griseus

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Transcription factor: CebR

Gene ID SGR_4739 (link to Genome Viewer)
Factor type LacI family
Pfam PF00356 (Bacterial regulatory proteins, lacI family )
Consensus seq. 5'-{TGGGAGC}{GCTCCCA}-3'
Comment CebR is a master regulator of cellulose/cellooligosaccharide catabolism. It is a LacI/GalR family regulator. CebR-disrupted starin formed very few aerial hyphae on lactose-containing medium.

Regulated Gene Sigma Regulation Absolute position Location Binding seq.(cis-element) Experimental evidence
cebE None Negative 5564510..5564540 +1:+31 AACGGCGCATGGGAGCGCTCCCACTCCAGGG Marushima K, et al. (2009): DB,qRT-PCR,EMSA,HM
cebR None Negative? 5569653..5569684 -40:-5 TCCCCTTCTTGGGAGCGCTCCCAATACACTGT Marushima K, et al. (2009): DB,qRT-PCR,EMSA,HM
bglC None Negative 5568107..5568137 -28:+7(from translation start site) CACTTCCCCAGGGAGCGCTCCCACATGACAG Marushima K, et al. (2009): DB,qRT-PCR,EMSA,HM
SGR_199 None Negative 202953..202983 -341:-310(from translation start site) ATCAGCGTGTGGGAGCGCTCCCAGATTCTCC Marushima K, et al. (2009): DB,qRT-PCR,EMSA,HM
SGR_199 None Negative 202758..202789 -536:-504(from translation start site) AGTGGGATGCGGGAGCGCTCCCCAATCTGTCA Marushima K, et al. (2009): DB,qRT-PCR,EMSA,HM
SGR_217 None Negative 227610..227639 -118:-89(from translation start site) ACGACGTGCGGGAGCGCTCCCATATGTCAT Marushima K, et al. (2009): DB,qRT-PCR,EMSA,HM
SGR_1971 None Negative 2327353..2327381 -313:-284(from translation start site) TCCCGGGAGGGGAGCGCTCCCAGGTGCCC Marushima K, et al. (2009): DB,qRT-PCR,EMSA,HM
SGR_2445 None Negative 2883476..2883507 -40:-9(from translation start site) CGTCGTCGATTGGGAGCGCTCCCACAGAAGGG Marushima K, et al. (2009): DB,qRT-PCR,EMSA,HM
SGR_6928 None Negative 8314828..8314858 -128:-98(from translation start site) GCGCCAGTTTGGGAGCGCTCCCACACGCACG Marushima K, et al. (2009): DB,qRT-PCR,EMSA,HM
SGR_6928 None Negative 8314741..8314771 -215:-185(from translation start site) GGCCATTGGTGGGAGCGCTCCAACAGCGCTC Marushima K, et al. (2009): DB,qRT-PCR,EMSA,HM




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Contact: Yuko Makita