DBSCR - Regulated genes

   Database of transcriptional regulation in Streptomyces coelicolor
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Regulated gene: hmgA

Operon: No data
Genes Gene ID Synonyms Direction Genome position Function
hmgA SCO1715 SCI11.04, hgd, hmgA + 1835784..1837109 putative homogentisate 1,2-dioxygenase

Promoters

Binding
factor		 Promoter
name		 Regulation Location Absolute position Binding seq.(cis-element) Experimental evidence
HpdA - Positive ND ND ND Zhang Y, et al. (2008): DB
Unknown_sigma - Promoter -50:+10 1835696..1835755 TCCTCTTGTGCCCTCTTGCGCGCGGGAAACCGCAATCCTACGGTGTGCCATAGGAATCGG Zhang Y, et al. (2008): S1

Comments:
HpdA Transcription of hmgA is activated by HpdA in the presence of thytosine. Zhang Y, et al. showed that mutation of hmgA gene increased the transcritpion of actII-ORF4.
Unknown_sigma -35/-10 motifs are defined based on the sequence homology with hmgA promoter in Pseudomonas putida.

Terminator

No Data

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Contact: Yuko Makita