DBSCR - Regulated genes

Database of transcriptional regulation in Streptomyces coelicolor

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Transcription factors

Regulated genes

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Regulated gene:

cefD

Operons: cefDE-pcd

Genes	Gene ID	Synonyms	Function
cefD
cefE
pcd

Reference:	Santamarta I, et al. (2002), Perez-Llarena FJ, et al. (1998)

Promoters

Binding factor	Promoter name	Regulation	Location	Binding seq.(cis-element)	Experimental evidence	Organism
CcaR	-	Positive	`-44:-4 (from translational start site)`	`TCGAGTC-N13-TCGATCG-N6-TCGAATT`	Santamarta I, et al. (2002): RG, GS, HM	S. clavuligerus
CcaR	-	Positive	`-354:-325 (from translational start site)`	`TCGATCT-N16-TCGATGG`	Santamarta I, et al. (2002): RG, GS, HM	S. clavuligerus
CcaR	-	Positive	`-195:-189 (from translational start site)`	`TCGAAAG`	Santamarta I, et al. (2002): RG, GS, HM	S. clavuligerus

Comments:
CcaR	CcaR protein is an activator controlling the expression of its own ccaR gene; additionally it activates expression of the cefD gene, which encodes the epimerase required for the middle steps of the pathway, and of the cmcI gene, encoding the late methoxylation reaction of the cephamycin pathway.
CcaR	CcaR protein is an activator controlling the expression of its own ccaR gene; additionally it activates expression of the cefD gene, which encodes the epimerase required for the middle steps of the pathway, and of the cmcI gene, encoding the late methoxylation reaction of the cephamycin pathway.
CcaR	CcaR protein is an activator controlling the expression of its own ccaR gene; additionally it activates expression of the cefD gene, which encodes the epimerase required for the middle steps of the pathway, and of the cmcI gene, encoding the late methoxylation reaction of the cephamycin pathway.

Terminator

No Data

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Contact: Yuko Makita