DBSCR - Regulated genes

   Database of transcriptional regulation in Streptomyces coelicolor

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Regulated gene: cefD

Operons: cefDE-pcd

Genes Gene ID Synonyms Function
cefD
cefE
pcd

Reference: Santamarta I, et al. (2002), Perez-Llarena FJ, et al. (1998)


Promoters

Binding
factor
Promoter
name
Regulation Location Binding seq.(cis-element) Experimental evidence Organism
CcaR - Positive -44:-4 (from translational start site) TCGAGTC-N13-TCGATCG-N6-TCGAATT Santamarta I, et al. (2002): RG, GS, HM
S. clavuligerus
CcaR - Positive -354:-325 (from translational start site) TCGATCT-N16-TCGATGG Santamarta I, et al. (2002): RG, GS, HM
S. clavuligerus
CcaR - Positive -195:-189 (from translational start site) TCGAAAG Santamarta I, et al. (2002): RG, GS, HM
S. clavuligerus

Comments:
CcaR CcaR protein is an activator controlling the expression of its own ccaR gene; additionally it activates expression of the cefD gene, which encodes the epimerase required for the middle steps of the pathway, and of the cmcI gene, encoding the late methoxylation reaction of the cephamycin pathway.
CcaR CcaR protein is an activator controlling the expression of its own ccaR gene; additionally it activates expression of the cefD gene, which encodes the epimerase required for the middle steps of the pathway, and of the cmcI gene, encoding the late methoxylation reaction of the cephamycin pathway.
CcaR CcaR protein is an activator controlling the expression of its own ccaR gene; additionally it activates expression of the cefD gene, which encodes the epimerase required for the middle steps of the pathway, and of the cmcI gene, encoding the late methoxylation reaction of the cephamycin pathway.


Terminator

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Contact: Yuko Makita