DBSCR - Transcription factor

Database of transcriptional regulation in Streptomyces

Home

GenBank ID	no data
Factor type	ND
Pfam	None
Consensus seq.	ND
Comment	CcaR is an autoregulatory protein that binds to the ccaR and cefD-cmcI promoters of the Cephamycin C-Clavulanic acid cluster in Streptomyces clavuligerus.

Regulated Gene	Sigma	Regulation	Location	Binding seq.(cis-element)	Experimental evidence	Organism
lat	None	Positive	`-50:-28(anti-sense strand)`	`GCAGGCTCTCTCGACCTTCTCCC`	Kyung YS, et al. (2001): GS, FT	S. clavuligerus
cefD	None	Positive	`-44:-4 (from translational start site)`	`TCGAGTC-N13-TCGATCG-N6-TCGAATT`	Santamarta I, et al. (2002): RG, GS, HM	S. clavuligerus
cefD	None	Positive	`-354:-325 (from translational start site)`	`TCGATCT-N16-TCGATGG`	Santamarta I, et al. (2002): RG, GS, HM	S. clavuligerus
cefD	None	Positive	`-195:-189 (from translational start site)`	`TCGAAAG`	Santamarta I, et al. (2002): RG, GS, HM	S. clavuligerus
cmcI	None	Positive	`-224:-196 (from translational start site)`	`TCGACCG-N15-TCGATGG`	Santamarta I, et al. (2002): RG, GS, HM	S. clavuligerus
cmcI	None	Positive	`-395:-366 (from translational start site)`	`TCGATCT-N16-TCGATGG`	Santamarta I, et al. (2002): RG, GS, HM	S. clavuligerus
ccaR	None	Positive	`-840:-815`	`GGAAAAACGTACCCCGGGGTCGGTTT`	Santamarta I, et al. (2002): RG, GS Santamarta I, et al. (2005): HM, DP, GS	S. clavuligerus