DBSCR - Regulated genes

   Database of transcriptional regulation in Streptomyces coelicolor

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Regulated gene: pikD

Operon: No data
Genes Gene ID Synonyms Function
pikD


Promoters

Binding
factor
Promoter
name
Regulation Location Binding seq.(cis-element) Experimental evidence Organism
AfsR-sv - Positive ND ND Maharjan S, et al. (2009): OV, RT-PCR
S. venezuelae

Comments:
AfsR-sv RT-PCR analysis was carried out to assess the expression levels of two representative genes: the ketosynthase (KS) gene and pikD. RT-PCR assays demonstrated that afsR-sv functions as a positive regulator and is involved in the regulation of pikromycin biosynthesis in S. venezuelae. Overexpression of afsR-sv in S. venezuelae seemed to activate the transcription of ketosynthase and a pathway-specific regulator, both resulting in the overproduction of pikromycin.


Terminator

No Data




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