DBSCR - Transcription factor

   Database of transcriptional regulation in Streptomyces

Transcription factors
Regulated genes
Revised TLS

Transcription factor: PimR

GenBank ID 152955875
Factor type ND
Pfam PF00486 (Transcriptional regulatory protein, C terminal ) PF03704 (Bacterial transcriptional activator domain )
Consensus seq. ND
Comment PimR represents the archetype of a new class of regulators, combining a Streptomyces antibiotic regulatory protein (SARP)-like Nterminal section with a C-terminal half homologous to guanylate cyclases and large ATP-binding regulators of the LuxR family. PimR activates the transcription of all the genes belonging to the pimaricin gene cluster but not its own transcription.

Regulated Gene Sigma Regulation Location Binding seq.(cis-element) Experimental evidence Organism
pimE None Positive ND ND Anton N, et al. (2004): DB, RT-PCR
S. natalensis


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Contact: Yuko Makita