DBSCR - Transcription factor

   Database of transcriptional regulation in Streptomyces coelicolor

Transcription factors
Regulated genes
Revised TLS

Transcription factor: FasR

Gene ID SCO2386 (link to ScoCyc)
Factor type ND
Pfam None
Consensus seq. ND
Comment A novel transcription factor, FasR (SCO2386), controls expression of fabDHPF operon and lies immediately upstream of fabD, in a cluster of genes that is highly conserved within actinomycetes. Expression of fab genes was downregulated in the fasR mutant, indicating a role for this transcription factor as an activator. FasR binds specifically to a DNA sequence containing fabDHPF promoter region, both in vivo and in vitro.

Regulated Gene Sigma Regulation Absolute position Location Binding seq.(cis-element) Experimental evidence
fabD None Positive 2559253..2559273 -87:-67(from translation start site) TTTTGTGCAGGGTCCACAAAA Xu D, et al. (2010): OV, HM, GS, qRT-PCR


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Contact: Yuko Makita