We have described a five-gene SoxR regulon in S. coelicolor whose products are predicted to encode an ABC transport protein (SCO7008 [ecaA]), two oxidoreductases (SCO2478 and SCO4266 [ecaD]), a monooxygenase (SCO1909[ecaB]), and an NAD-dependent epimerase/dehydratase(SCO1178 [ecaC]).