DBSCR - Regulated genes

   Database of transcriptional regulation in Streptomyces coelicolor

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Regulated gene: phoA

Operon: No data
Genes Gene ID Synonyms Direction Genome position Function
phoA SCO2286 SCC75A.32c, phoA - 2456145..2457821 putative alkaline phosphatase


Promoters

Binding
factor
Promoter
name
Regulation Location Absolute position Binding seq.(cis-element) Experimental evidence
HrdB phoA-p1 Promoter -50:+10 2457865..2457924 CCGGAACTCATCCGTCCGACACGTGATCGCCATGTCCGTGCCAAACCGGGGTCGTTCCCG Apel AK, et al. (2007): PE, HM
Unknown_sigma phoA-p2 Promoter -50:+10 2457837..2457896 GCCATGTCCGTGCCAAACCGGGGTCGTTCCCGGCGCTTCGAATGCCCCTTGCAACCACCG Apel AK, et al. (2007): PE
PhoP phoA-p1 Positive -134:-93 2457939..2457980 CTCGTCGGTGGTTCTCACGGTGTTCATGACTCGGCAGCGTAC Apel AK, et al. (2007): DB, GS, FT
PhoP phoA-p2 Positive -107:-66 2457939..2457980 CTCGTCGGTGGTTCTCACGGTGTTCATGACTCGGCAGCGTAC Apel AK, et al. (2007): DB, GS, FT

Comments:
HrdB Expression of phoA-p1 is stronger than phoA-p2. PhoA promoter is strongly activated under low phosphate concentrations.
PhoP Both phoA-p1 and phoA-p2 promoters are likely to be regulated bo phosphate availability.
PhoP Both phoA-p1 and phoA-p2 promoters are likely to be regulated bo phosphate availability.


Terminator

No Data

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Contact: Yuko Makita