DBSCR - Regulated genes

   Database of transcriptional regulation in Streptomyces coelicolor

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Regulated gene: redZ

Operon: No data
Genes Gene ID Synonyms Direction Genome position Function
redZ SCO5881
- 6438206..6438859 response regulator


Promoters

Binding
factor
Promoter
name
Regulation Location Absolute position Binding seq.(cis-element) Experimental evidence
AbsA2 - Negative ND ND ND McKenzie NL, et al. (2007): ChIP, DB, GS
RedZ - Negative ND ND ND White J, et al. (1997): S1, DB
Unknown_sigma - Promoter -50:+10 6438962..6439021 CCTCGCAAGCCCCTCTCCAAGTGTGCACACGCGTGCTAAGTTTGGCCGCATGAGGCATAT Guthrie EP, et al. (1998): S1
WblA - Negative ND ND ND Kang SH, et al. (2007): AR, OV(RT-PCR)
DasR - Negative -212:-172(from translation start site) 6439032..6439071 ACAAGATCTTCTTGAGGTGGAAACCACTTCGTATCAGTCT Rigali S, et al. (2008): HM, GS, sqRT-PCR
SCO1712 - Negative ND ND ND Lee HN, et al. (2010): DB, OV(by RT-PCR)
Kang SH, et al. (2007): AR

Comments:
DasR The dre site upstream from redZ is situated about 50 bp upstream from the -35 sequence of the redZ promoter. DasR bound to the dre elements for the actII-ORF4, redZ and crr-ptsI promoter regions, but not to the cis-acting element of Crp. Semiquantitative reverse transcription-PCR (RT-PCR) analyses further showed upregulation of actII-ORF4 and redZ in the dasR mutant.
SCO1712 Transcripts encoded by pathway-specific activator genes such as actII-ORF4, redD/Z, and cdaR were all significantly increased at both time points from S. coelicolor M145-SCO1712. As expected, an opposite transcription pattern was observed in the SCO1712-overexpressing S. coelicolor M145 strain.


Terminator

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Contact: Yuko Makita