DBSCR - Regulated genes

   Database of transcriptional regulation in Streptomyces coelicolor
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Regulated gene: lat

Operon: No data
Genes Gene ID Synonyms Function
lat

Promoters

Binding
factor		 Promoter
name		 Regulation Location Binding seq.(cis-element) Experimental evidence Organism
Unknown_sigma - Promoter -50:+10 CGTCCGAGAGAGCTGGAAGAGGGGTCCAAGAGCATGGTGGGTCATTATTGTGATCCTAAA Kyung YS, et al. (2001): HM
 S. clavuligerus
CcaR - Positive -50:-28(anti-sense strand) GCAGGCTCTCTCGACCTTCTCCC Kyung YS, et al. (2001): GS, FT
 S. clavuligerus

Comments:
Unknown_sigma The importance of the alpha-aminoadipic acid flux in the biosynthesis led to investigation of the role of lat coding for lysene-epsilon-amino-transferase (LAT), which is the first enzyme responsible for the conversion of lysine to alpha-aminoadipic acid.
CcaR CcaR is a DNA-binding protein that controls the transcription of lat by binding adjacent to the -35 region of the target gene promoter.

Terminator

No Data

DBSCR:

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Contact: Yuko Makita