DBSCR - Transcription factor

Database of transcriptional regulation in Streptomyces

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GenBank ID	152955874
Factor type	ND
Pfam	PF00196 (Bacterial regulatory proteins, luxR family )
Consensus seq.	ND
Comment	PimM combines an N-terminal PAS domain with a C-terminal helix-turn-helix (HTH) motif of the LuxR type. PimM is a positive regulator of pimaricin biosynthesis. PimM plays its regulatory role independently of PimR, the first pathway-specific regulator of pimaricin biosynthesis.

Regulated Gene	Sigma	Regulation	Location	Binding seq.(cis-element)	Experimental evidence	Organism
pimK	None	Positive	`-45:-22`	`GCCAAGTCTAAGGATTTCCCGACG`	Anton N, et al. (2007): DB, OV, RT-PCR Santos-Aberturas J, et al. (2011): DP, GS, FT, HM, RACE	S. natalensis
pimA	None	Positive	`-41:-18`	`ATCTAGGGGTTTTCCGGTGTGCGG`	Anton N, et al. (2007): DB, OV, RT-PCR Santos-Aberturas J, et al. (2011): DP, GS, FT, HM, RACE	S. natalensis
pimE	None	Positive	`-46:-23`	`GTACCTCTGGCATTTCCCCCAGTC`	Anton N, et al. (2007): DB, OV, RT-PCR Santos-Aberturas J, et al. (2011): DP, GS, FT, HM, RACE	S. natalensis
pimJ	None	Positive	`-49:-24`	`TGTGCCCGGAATTTCTTGACATCATG`	Anton N, et al. (2007): DB, OV, RT-PCR Santos-Aberturas J, et al. (2011): DP, GS, FT, HM, RACE	S. natalensis
pimI	None	Positive	`-45:-23`	`GGATACTAGGTGTTTTCCGGCAT`	Anton N, et al. (2007): DB, OV, RT-PCR Santos-Aberturas J, et al. (2011): DP, GS, FT, HM, RACE	S. natalensis
pimS2	None	Positive	`-44:-22`	`GAATCTAGGGAATTCCATGACAA`	Anton N, et al. (2007): DB, OV, RT-PCR Santos-Aberturas J, et al. (2011): DP, GS, FT, HM, RACE	S. natalensis
pimD	None	Positive	`-42:-20`	`GTGTAGGGATTTCCTGGTCCGGA`	Anton N, et al. (2007): DB, OV, RT-PCR Santos-Aberturas J, et al. (2011): DP, GS, FT, HM, RACE	S. natalensis
pimS1	None	Positive	`-42:-19`	`AACTAGGGAAACCCGCAGTCCACC`	Anton N, et al. (2007): DB, OV, RT-PCR Santos-Aberturas J, et al. (2011): DP, GS, FT, HM, RACE	S. natalensis