DBSCR - Transcription factor

   Database of transcriptional regulation in Streptomyces coelicolor

Home
Transcription factors
Regulated genes
Revised TLS
Search
Contacts

Transcription factor: SCO3201

Gene ID SCO3201 (link to ScoCyc)
Factor type TetR-family
Pfam None
Consensus seq. ND
Comment SCO3201 was shown to negatively regulate its own transcription, and its DNA binding motif was found to overlap its -35 promoter sequence. The direct and functional interaction of SCO3201 with the promoter region of scbA, a gene under the positive control of the TetR-like regulator, ScbR, was indeed demonstrated by in vitro as well as in vivo approaches.

Regulated Gene Sigma Regulation Absolute position Location Binding seq.(cis-element) Experimental evidence
SCO3201 None Negative 3509954..3510010 -56:+1 ACCCCGGGGTGGCCCGCCGAATGGCAGATTCTGCCACAGCGGCATAGCCTGCCGAAG Xu D, et al. (2010): OV, DB, GS, FT, RACE, RT-PCR
scbA None Positive 6891207..6891263 -39:+18 AGGATAGAAAAAAAACCGCTCAGTCTGTATCTTAACGTTCGCGCATACAGAACAGCT Xu D, et al. (2010): OV, HM, GS, RT-PCR




DBSCR:

Copyright: BASE, RIKEN
Contact: Yuko Makita