DBSCR - Regulated genes

   Database of transcriptional regulation in Streptomyces coelicolor
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Regulated gene: scbA

Operon: No data
Genes Gene ID Synonyms Direction Genome position Function
scbA SCO6266 SCAH10.31, scbA + 6891293..6892237 ScbA protein

Promoters

Binding
factor		 Promoter
name		 Regulation Location Absolute position Binding seq.(cis-element) Experimental evidence
HrdB? - Promoter -50:+10 6891196..6891255 CTCCCCCGGGAAGGATAGAAAAAAAACCGCTCAGTCTGTATCTTAACGTTCGCGCATACA Takano E, et al. (2001): S1
ScbR - Positive -40:+5 6891206..6891250 AAGGATAGAAAAAAAACCGCTCAGTCTGTATCTTAACGTTCGCGC Takano E, et al. (2001): S1, GS, FT
SCO3201 - Positive -39:+18 6891207..6891263 AGGATAGAAAAAAAACCGCTCAGTCTGTATCTTAACGTTCGCGCATACAGAACAGCT Xu D, et al. (2010): OV, HM, GS, RT-PCR

Comments:
SCO3201 SCO3201 was shown to negatively regulate its own transcription, and its DNA binding motif was found to overlap its -35 promoter sequence. The direct and functional interaction of SCO3201 with the promoter region of scbA, a gene under the positive control of the TetR-like regulator, ScbR, was indeed demonstrated by in vitro as well as in vivo approaches.

Terminator

No Data

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Contact: Yuko Makita