DBSCR - Regulated genes

   Database of transcriptional regulation in Streptomyces coelicolor
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Regulated gene: SCO7682

Operon: No data
Genes Gene ID Synonyms Direction Genome position Function
SCO7682 SCO7682 SC4C2.17 + 8506283..8512972 putative non-ribosomal peptide synthase

Promoters

Binding
factor		 Promoter
name		 Regulation Location Absolute position Binding seq.(cis-element) Experimental evidence
AbsC - Negative -103:-64(from translation start site) 8506180..8506219 GTGATTACGATGTGAACTATAGAAATGATAATCATTTCTA Hesketh A, et al. (2009): AR, DB, FT, GS, OV, qRT-PCR
Zur - Negative -89:-68(from translation start site) 8506194..8506215 AACTATAGAAATGATAATCATT Hesketh A, et al. (2009): AR, DB, FT, GS, OV, qRT-PCR
Kallifidas D, et al. (2010): AR, DB, GS, qPCR

Comments:
AbsC An AbsC binding site was identified in a divergent promoter region within the coelibactin biosynthetic gene cluster, adjacent to a putative Zur binding site. Repression of the coelibactin gene cluster by both AbsC and Zur appears to be required to maintain appropriate intracellular levels of zinc in S. coelicolor.
Zur The Zinc-Responsive Regulator Zur Controls Expression of the Coelibactin Gene Cluster in Streptomyces coelicolor.

Terminator

No Data

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Contact: Yuko Makita