DBSCR - Transcription factor

Database of transcriptional regulation in Streptomyces coelicolor

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Gene ID	SCO2508 (link to ScoCyc)
Factor type	ND
Pfam	PF01475 (Ferric uptake regulator family )
Consensus seq.	tcATGAAANTCATTTTCANNA
Comment	A zinc-specific negative regulator of the Fur family, regulates genes for zinc transport systems to maintain zinc homeostasis.
Link to	Weight matrix & Motif alignment

Regulated Gene	Sigma	Regulation	Absolute position	Location	Binding seq.(cis-element)	Experimental evidence
rpmB2	None	Negative	`3791104..3791149`	`-20:+25 (from rpmB2 promoter)`	`GCTGCTATCTTACTGAAAATGAATTCCATTAACAGCTAGGACCCGT`	Owen GA, et al. (2007): DB, FT Shin JH, et al. (2007): DB, FT
rpmG2	None	Negative	`3791104..3791149`	None	`ACGGGTCCTAGCTGTTAATGGAATTCATTTTCAGTAAGATAGCAGC`	Owen GA, et al. (2007): DB, FT Shin JH, et al. (2007): DB, FT
rpmF2	None	Negative	`457412..457461`	`-50:-1`	`GGACACGACACATTCAACATGAACATCGTTTTCATGTAGGGTCGGGGTTC`	Owen GA, et al. (2007): DB, FT
rpmG3	None	Negative	ND	ND	ND	Owen GA, et al. (2007): DB
znuA	None	Negative	`2703964..2704023`	`-40:+20`	`TTGTTGACAACGGTTTCCATATTTGTTGAAAATGAGTGTCATGAACGTACGACGACGCCG`	Owen GA, et al. (2007): DB, FT Shin JH, et al. (2007): DB, FT
SCO7682	None	Negative	`8506194..8506215`	`-89:-68(from translation start site)`	`AACTATAGAAATGATAATCATT`	Hesketh A, et al. (2009): AR, DB, FT, GS, OV, qRT-PCR Kallifidas D, et al. (2010): AR, DB, GS, qPCR
SCO7676	None	Negative	`8498987..8499008`	ND	`GATGAATGTCGTTTTCTATTAA`	Kallifidas D, et al. (2010): AR, DB, GS, qPCR
SCO0475	None	Negative	`497371..497392`	ND	`GTTGAACATGATTTTCATTGTA`	Kallifidas D, et al. (2010): AR, DB, GS, qPCR