DBSCR - Regulated genes

   Database of transcriptional regulation in Streptomyces coelicolor
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Regulated gene: adpA

Operons: adpA-ornA

Genes Gene ID Synonyms Direction Genome position Function
adpA SGR_4742
- 5572625..5573842 transcriptional regulator
ornA SGR_4741
- 5572009..5572614 oligoribonuclease

Operon evidence: Genome analysis
Reference:

Promoters

Binding
factor		 Promoter
name		 Regulation Location Absolute position Binding seq.(cis-element) Experimental evidence
ArpA - Negative -40:+10 5574096..5574145 CGCCCACCAGGCAGGAACGGACCGCGCGGTACGCTTTCACCCGACGCGGA Ohnishi Y, et al. (1999): GS, HM
Unknown_sigma - Promoter -50:+20 5574086..5574155 GACACCCCACCGCCCACCAGGCAGGAACGGACCGCGCGGTACGCTTTCACCCGACGCGGACGGGCCACGT Ohnishi Y, et al. (1999): S1
AdpA adpA-site1 Negative -139:-80 5574183..5574241 GCGCCCGGCGTGACCGGATACAGCACACGCAACCAATGGTTTTAAGCCAACTTCACCCG Kato JY, et al. (2005): DB, FT, DP
AdpA adpA-site2A Negative -68:-40 5574143..5574171 CTTCGCGGGATGGCCGGACACCCCACCGC Kato JY, et al. (2005): DB, FT, DP
AdpA adpA-site2B Negative -44:-15 5574120..5574147 ACCGCCCACCAGGCAGGAACGGACCGCG Kato JY, et al. (2005): DB, FT, DP
AdpA adpA-site2C Negative +1:+27 5574079..5574105 CCGACGCGGACGGGCCACGTTGTCGAA Kato JY, et al. (2005): DB, FT, DP
AdpA adpA-site3 Negative +66:+95 5574011..5574040 TGATCGAACGCTTCACGCCACGTTTCCTTA Kato JY, et al. (2005): DB, FT, DP
Unknown_sigma - Promoter -50:+10 5574096..5574155 GACACCCCACCGCCCACCAGGCAGGAACGGACCGCGCGGTACGCTTTCACCCGACGCGGA Kato JY, et al. (2005): S1

Comments:
ArpA A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolacetone) at an extremely low concentration triggers streptomycin production and aerial mycelium formation by binding a repressor, ArpA, and dissociating it from the DNA.

Terminator

No Data

Overview

DBSCR:

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Contact: Yuko Makita