DBSCR - Transcription factor

   Database of transcriptional regulation in Streptomyces

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Transcription factor: AreB

GenBank ID 154425140
Factor type ND
Pfam PF00392 (Bacterial regulatory proteins, gntR family ) PF01614 (Bacterial transcriptional regulator )
Consensus seq. ND
Comment The areB gene, encoding this protein, is located upstream and in opposite orientation to the leuCD operon of S. clavuligerus; it encodes a 239-amino-acid protein of the IclR family with a helix-turn-helix motif at the N-terminal region.

Regulated Gene Sigma Regulation Location Binding seq.(cis-element) Experimental evidence Organism
ccaR None Negative -840:-815 GGAAAAACGTACCCCGGGGTCGGTTT Santamarta I, et al. (2005): HM, DP, GS
Santamarta I, et al. (2007): DB, GS, FT, HM, RT-PCR
S. clavuligerus
areB None Positive -39:-26 GAACTTTGAACTTG Santamarta I, et al. (2007): S1, PE, DB, GS, FT, HM, RT-PCR
S. clavuligerus
leuC None Positive -91:-78 CAAGTTCAAAGTTC Santamarta I, et al. (2007): S1, PE, DB, GS, FT, HM, RT-PCR
S. clavuligerus
brp None Positive -86:-61 (from translational start site) TGTCATTCAGACCCTTCGGTTTCTTT Santamarta I, et al. (2005): HM, DP, GS
Santamarta I, et al. (2007): S1, PE, DB, GS, FT, HM, RT-PCR
S. clavuligerus




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